Diagnostic Microbiology & Infectious Disease
Volume 50, Issue 4 , Pages 231-235 , December 2004

Susceptibility of Helicobacter pylori isolates to the antiadhesion activity of a high-molecular-weight constituent of cranberry

  • Haim Shmuely

      Affiliations

    • Helicobacter pylori Research Institute, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel
    • Corresponding Author InformationCorresponding author. Tel.: +97-23-937-6301; fax: +97-23-922-1605.
    • ,
  • Ora Burger

      Affiliations

    • Faculty of Food Engineering and Biotechnology, Israel Institute of Technology-Technion, Haifa, Israel
    • ,
  • Itzhak Neeman

      Affiliations

    • Faculty of Food Engineering and Biotechnology, Israel Institute of Technology-Technion, Haifa, Israel
    • ,
  • Jacob Yahav

      Affiliations

    • Helicobacter pylori Research Institute, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel
    • ,
  • Zmira Samra

      Affiliations

    • Helicobacter pylori Research Institute, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel
    • ,
  • Yaron Niv

      Affiliations

    • Helicobacter pylori Research Institute, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel
    • ,
  • Nathan Sharon

      Affiliations

    • Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot, Israel
    • ,
  • Erwin Weiss

      Affiliations

    • Department of Prosthodontics, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    • ,
  • Abed Athamna

      Affiliations

    • Triangle Research and Development Center, Kfar Qaraa, Israel
    • ,
  • Miriam Tabak

      Affiliations

    • Faculty of Food Engineering and Biotechnology, Israel Institute of Technology-Technion, Haifa, Israel
    • ,
  • Itzhak Ofek

      Affiliations

    • Department of Human Microbiology, Tel Aviv University, Tel Aviv, Israel

Received 16 March 2004 ,Accepted 18 August 2004.

References 

  1. Avorn J, Monane M, Gruwitz JH, Glynn RJ, Choodnovskiy I, Lipsitz A. Reduction of bacteriuria and pyuria after ingestion of cranberry juice. JAMA. 1994;271:751–754
  2. Burger O, Ofek I, Tabak M, Weiss E, Sharon N, Neeman I. A high molecular-weight constituent of cranberry juice inhibits Helicobacter pylori adhesion to human gastric mucus. FEMS Immunol Med Microbiol. 2000;29:295–303
  3. de Boer WA, Tytgat GNJ. 90% cure: which anti-Helicobacter therapy can achieve this goal?. Am J Gastroenterol. 1995;90:1381–1382
  4. Dore MP, Leandro G, Realdi G, Sepulveda AR, Graham DY. Effect of pretreatment antibiotic resistance to metronidazole and clarithromycin on outcome of Helicobacter pylori therapy: a meta-analytical approach. Dig Dis Sci. 2000;45:68–76
  5. Dorrell N, Crabtree JE, Wren BW. Host-bacterial interactions and the pathogenesis of Helicobacter pylori infection. Trends Microbiol. 1998;6:379–381
  6. Fang H, Edlund C, Hedberg M, Nord CE. New findings in beta-lactam and metronidazole resistant Bacteroides fragilis group. Int J Antimicrob Agents. 2002;9:361–370
  7. Graham DY. A reliable cure for H. pylori infection?. Gut. 1996;37:154–163
  8. Graham DY, de Boer WA, Tytgat GN. Choosing the best anti-Helicobacter pylori therapy: effect of antimicrobial resistance. Am J Gastroenterol. 1996;91:1072–1076
  9. Kontiokari T, Sundqvist K, Nuutinen M, Pokka T, Koskela M, Uhari M. Randomized trial of cranberry-lingonberry juice and Lactobacillus GG drink for the prevention of urinary tract infections in women. Br Med J. 2001;322:1–5
  10. Martınez-Martınez L, Hernandez-Alles S, Albertı S, Tomas JM, Benedi VJ, Jacoby GA. In vivo selection of porin-deficient mutants of Klebsiella pneumoniae with increased resistance to cefoxitin and expanded-spectrum cephalosporins. Antimicrob Agents Chemother. 1996;40:342–348
  11. Ofek I, Goldhar J, Zafriri D, Lis H, Adar R, Sharon N. Anti-Escherichia coli adhesion activity of cranberry and blueberry juices. N Engl J Med. 1991;324:1599
  12. Ofek I, Goldhar J, Sharon N. Anti-Escherichia coli adhesion activity of cranberry and blueberry juices. In:  Kahane I,  Ofek I editor. Toward Anti-Adhesion Therapy of Microbial Diseases. London: Plenum; 1996;p. 179–184 408
  13. Osata MS, Reddy R, Graham DY. Metronidazole and clarithromycin resistance amongst Helicobacter pylori isolates from a large metropolitan hospital in the United States. Int J Antimicrobial Agents. 1999;12:334–341
  14. Samra Z, Shmuely H, Niv Y, Dinari G, Passaro DJ, Geler A, et al. Resistance of Helicobacter pylori isolates in Israel to metronidazole, clarithromycin, tetracycline, amoxicillin, and cefixime. J Antimicrobial Chemother. 2002;49:1023–1026
  15. Turner P, Edwards R, Weston V, Gazis A, Ispahani P, Greenwood D. Simultaneous resistance to metronidazole, co-amoxiclav, and imipenem in clinical isolates of Bacteroides fragilis. Lancet. 1995;345:1275–1277
  16. Van der Wouden EJ, Thijs JC, Zwet AA, Kooy A, Kleibeuker JH. The influence of metronidazole resistance on the efficacy of ranitidine bismuth citrate triple therapy regimens for Helicobacter pylori infection. Aliment Pharmacol Ther. 1999;13:297–302
  17. Weiss EI, Lev-Dor R, Kashman Y, Goldhar J, Sharon N, Ofek I. Inhibiting interspecies coaggregation of plaque bacteria with cranberry juice constituent. J Am Dent Assoc. 1998;129:1719–1723
  18. Zafriri D, Ofek I, Adar R, Pocino M, Sharon N. Inhibitory activity of cranberry juice on adherence of type 1 and type P fimbriated Escherichia coli to eucaryotic cells. Antimicrob Agents Chemother. 1989;33:92–98

PII: S0732-8893(04)00176-2

doi: 10.1016/j.diagmicrobio.2004.08.011

Diagnostic Microbiology & Infectious Disease
Volume 50, Issue 4 , Pages 231-235 , December 2004

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