Diagnostic Microbiology & Infectious Disease
Volume 54, Issue 1 , Pages 79-82, January 2006

High rates of erythromycin and clindamycin resistance among OBGYN isolates of group B Streptococcus☆

  • Linda P. DiPersio

      Affiliations

    • Falor Division of Surgical Research, Summa Health System, Akron, OH 44304, USA
    • ,
  • Joseph R. DiPersio

      Affiliations

    • Department of Pathology and Laboratory Medicine, Summa Health System, Akron, OH 44304, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1-330-375-3667; fax: +1-330-375-4874.

Received 22 April 2005; accepted 29 July 2005.

Abstract 

In vitro susceptibility testing on 200 Streptococcus agalactiae strains isolated during a 4-year period from vaginal/rectal specimens demonstrated a very high resistance rate for both erythromycin (54%) and clindamycin (33%). Methylase genes erm(B) and erm(TR) and efflux genes mef(E) and mef(A) were detected. Pulsed-field gel electrophoresis showed evidence of both clonal spread and multiclonal dissemination of resistant strains. All but 3 of 200 isolates were susceptible to telithromycin.

Keywords: Streptococcus agalactiae, Methylase genes, Erythromycin

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☆ This work was presented in part at the 2004 General Meeting, American Society for Microbiology, May 2004 (Abstract A-006).

PII: S0732-8893(05)00193-8

doi:10.1016/j.diagmicrobio.2005.07.003

Diagnostic Microbiology & Infectious Disease
Volume 54, Issue 1 , Pages 79-82, January 2006

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