Diagnostic Microbiology & Infectious Disease
Volume 65, Issue 4 , Pages 431-434 , December 2009

Polymyxin B and colistimethate are comparable as to efficacy and renal toxicity

  • Maura S. Oliveira

      Affiliations

    • Department of Infection Control of Hospital das Clínicas, Rua Dr. Ovídio Pires de Campos, São Paulo-SP 05403-010, Brazil
    • ,
  • Gladys V.B. Prado

      Affiliations

    • Department of Infection Control of Hospital das Clínicas, Rua Dr. Ovídio Pires de Campos, São Paulo-SP 05403-010, Brazil
    • ,
  • Silvia F. Costa

      Affiliations

    • Department of Infectious Diseases and LIM-54, University of São Paulo, Av. Dr. Enéas de Carvalho Aguiar, 470, São Paulo-SP 05403-000, Brazil
    • ,
  • Renato S. Grinbaum

      Affiliations

    • Department of Infection Control of Hospital do Servidor Público Estadual de São Paulo, Avenida Ibirapuera, 981, São Paulo-SP 04029-000, Brazil
    • ,
  • Anna S. Levin

      Affiliations

    • Department of Infection Control of Hospital das Clínicas, Rua Dr. Ovídio Pires de Campos, São Paulo-SP 05403-010, Brazil
    • Department of Infectious Diseases and LIM-54, University of São Paulo, Av. Dr. Enéas de Carvalho Aguiar, 470, São Paulo-SP 05403-000, Brazil
    • Corresponding Author InformationCorresponding author. Tel.: +55-11-3069-7066; fax: +55-11-3069-7066.

Received 7 April 2009 ,Accepted 15 July 2009.

References 

  1. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P Acute Dialysis Quality Initiative workgroup. Acute renal failure—definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit. Care. 2004;4:R204–R212
  2. Falagas ME, Kasiakou SK. Toxicity of polymyxins: a systematic review of the evidence from old and recent studies. Crit. Care. 2006;10:R27
  3. Garner JS, Jarvis WR, Emori TG, Horan TC, Hughes JM. CDC definitions for nosocomial infections. Am. J. Infect. Control. 1988;16:128–140
  4. Levin AS. Treatment of Acinetobacter spp infections. Expert Opin. Pharmacother. 2003;4:1289–1296
  5. Li J, Nation RL, Turnidge JD, Milne RW, Coulthard K, Rayner CR, et al. Colistin: the re-emerging antibiotic for multidrug-resistant Gram-negative bacterial infections. Lancet Infect. Dis. 2006;9:589–601
  6. Michalopoulos A, Falagas ME. Colistin and polymyxin B in critical care. Crit. Care Clin. 2008;24:377–391
  7. National Committee for Clinical Laboratory Standards. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard—fourth edition, M7-A4. Wayne, PA: NCCLS; 1996;
  8. Oliveira MS, Prado GV, Costa SF, Grinbaum RS, Levin AS. Ampicillin/sulbactam compared with polymyxins for the treatment of infections caused by carbapenem-resistant Acinetobacter spp. J. Antimicrob. Chemother. 2008;61:1369–1375
  9. Zavascki AP, Goldani LZ, Li J, Nation RL. Polymyxin B for the treatment of multidrug-resistant pathogens: a critical review. J. Antimicrob. Chemother. 2007;60:1206–1215

PII: S0732-8893(09)00298-3

doi: 10.1016/j.diagmicrobio.2009.07.018

Diagnostic Microbiology & Infectious Disease
Volume 65, Issue 4 , Pages 431-434 , December 2009

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