Diagnostic Microbiology & Infectious Disease
Volume 65, Issue 4 , Pages 439-446, December 2009

Diversity of the blaSHV genes

  • Nuno Mendonça

      Affiliations

    • Antibiotic Resistance Unit, Department of Infectious Diseases, National Institute of Health Dr. Ricardo Jorge, 1649-016 Lisbon, Portugal
    • ,
  • Marie-Hélène Nicolas-Chanoine

      Affiliations

    • Inserm, U-773, Faculté de Médecine D. Diderot, Université Paris 7, Paris, France
    • ,
  • Manuela Caniça

      Affiliations

    • Antibiotic Resistance Unit, Department of Infectious Diseases, National Institute of Health Dr. Ricardo Jorge, 1649-016 Lisbon, Portugal
    • Corresponding Author InformationCorresponding author. Tel.: +351-217519246; fax: +351-217519246.

Received 25 November 2008; accepted 11 August 2009. published online 22 September 2009.

Abstract 

We investigated the diversity of nucleotide sequences of 297 SHV-encoding genes, based on nucleotide synonymous mutations and the presence or absence of the nonsynonymous mutation T92A. The analysis of this diversity allowed us to develop and propose a classification to differentiate the nucleotide sequence variants of the blaSHV genes.

Keywords: Molecular diversity, Nucleotide sequence, Sequence variant, blaSHV gene

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PII: S0732-8893(09)00334-4

doi:10.1016/j.diagmicrobio.2009.08.005

Diagnostic Microbiology & Infectious Disease
Volume 65, Issue 4 , Pages 439-446, December 2009

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