Diagnostic Microbiology & Infectious Disease
Volume 65, Issue 4 , Pages 450-453, December 2009

Usefulness and influence of age of a novel Rapid HpStAR™ stool antigen for the diagnosis of Helicobacter pylori infection in children

  • Nicolas Kalach

      Affiliations

    • Clinique Pédiatrique Saint Antoine, Hôpital Saint Vincent de Paul, Université Catholique, Boulevard de Belfort, 59020 Lille, France
    • Department of Pediatrics-Neonatology, Hôpital Cochin-Saint Vincent de Paul, Université Paris Descartes, 75674 Paris Cedex 14, France
    • ,
  • Eric Dehecq

      Affiliations

    • Department of Microbiology, Université Catholique, Boulevard de Belfort, 59020 Lille, France
    • ,
  • Pierre Gosset

      Affiliations

    • Department of Pathology, Université Catholique, Boulevard de Belfort, 59020 Lille, France
    • ,
  • Anne Decoster

      Affiliations

    • Department of Microbiology, Université Catholique, Boulevard de Belfort, 59020 Lille, France
    • ,
  • Michel Bergeret

      Affiliations

    • Department of Bacteriology, Hôpital Cochin-Saint Vincent de Paul, Université Paris Descartes, 75679 Paris Cedex 14, France
    • ,
  • Christophe Dupont

      Affiliations

    • Department of Pediatrics-Neonatology, Hôpital Cochin-Saint Vincent de Paul, Université Paris Descartes, 75674 Paris Cedex 14, France
    • ,
  • Josette Raymond

      Affiliations

    • Department of Bacteriology, Hôpital Cochin-Saint Vincent de Paul, Université Paris Descartes, 75679 Paris Cedex 14, France
    • Corresponding Author InformationCorresponding author. Tel.: +33-1-58 41 15 25; fax: +33-1-58 41 15 48.

Received 3 June 2009; accepted 14 August 2009. published online 22 September 2009.

Abstract 

A novel rapid monoclonal enzyme immunoassay stool antigen for Helicobacter pylori detection (Rapid HpStAR™) was evaluated in 16 infected and 92 noninfected children. The overall sensitivity, specificity, and positive and negative predictive values were 87.5%, 97.8%, 87.5%, and 97.8%, respectively, with an accuracy of 96.2%. The negative predictive value was good in all age groups, reaching 100% in younger children.

Keywords: H. pylori, Diagnosis, Children

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PII: S0732-8893(09)00350-2

doi:10.1016/j.diagmicrobio.2009.08.008

Diagnostic Microbiology & Infectious Disease
Volume 65, Issue 4 , Pages 450-453, December 2009

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