Characterization of plasmids encoding CMY-2 AmpC β-lactamases from Escherichia coli in Canadian intensive care units☆☆☆
Received 14 May 2009; accepted 14 August 2009. published online 24 September 2009.
Abstract
The dissemination of CMY-2 AmpC β-lactamases among Escherichia coli in Canadian intensive care units occurs through a combination of clonal spread of virulent strains and the horizontal transfer of genetically similar IncI1, IncA/C, and IncK/B plasmids.
aDepartment of Medical Microbiology, Faculty of Medicine, University of Manitoba, Winnipeg, Canada R3A 1R9
bDepartment of Clinical Microbiology, Health Sciences Centre, Winnipeg, Canada R3A 1R9
cNational Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada R3E 3R2
Corresponding author. Department of Clinical Microbiology, Health Sciences Centre, Winnipeg, Manitoba, Canada R3A 1R9. Tel.: +1-204-787-4684; fax: +1-204-787-4699.
☆ This article was presented in part at the American Society for Microbiology 108th General Meeting (2008) in Boston, MA.
☆☆ Patricia Baudry is supported by the Winnipeg Health Sciences Centre Department of Research, the Winnipeg Health Sciences Centre Foundation, and the Manitoba Health Research Council. This research is funded in part by Abott, Bayer Canada, Bristol-Myers Squibb, Janssen-Ortho, Merck Frosst, Sanofi-Aventis, and Wyeth.
ABSTRACT