Genotypes, superantigen gene profiles, and presence of exfoliative toxin genes in clinical methicillin-susceptible Staphylococcus aureus isolates

Received 1 May 2009; accepted 23 August 2009. published online 15 October 2009.

Abstract

We compared genotype and virulence gene profiles for strains from carriers with autologous invasive infection (n = 56), nasal isolates from matched carriers (n = 108), and invasive strains from noncarriers (n = 34). Superantigen gene profiles and presence of exfoliative toxin genes A and D were associated with clonal complex rather than with invasive disease.

Keywords: Staphylococcus aureus, Superantigen genes, Bacteraemia, Clonal complexes

a Laboratory for Medical Microbiology, Maasstad Hospital, 3078 HT Rotterdam, The Netherlands

b Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, University Medical Center, 3015 CE Rotterdam, The Netherlands

Corresponding author. Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, University Medical Center, 3015 CE Rotterdam, The Netherlands. Tel.: +31-10-7033510; fax: +31-10-7033875.

PII: S0732-8893(09)00360-5

doi:10.1016/j.diagmicrobio.2009.08.021

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