Volume 66, Issue 2 , Pages 169-174, February 2010
Imported malaria in children: incidence and risk factors for severity☆
Abstract
To assess the incidence of imported malaria in children and to determine the frequency of delayed diagnosis and risk factors for severe malaria, we performed a retrospective multicenter cohort study in the northern region of France and included all children with a positive test for malaria from 2000 to 2006. The incidence of imported malaria in children <18 years, the frequency of a delayed diagnosis, and the risk factors for severe malaria were determined. The study identified 133 children with imported malaria. The mean incidence of this disease was 1.9/100 000 children <18 years (95% confidence interval [CI], 1.6–2.2). Detailed data were available for 120 children. Disease was considered severe in 19% of cases. The diagnosis was delayed (≥1 day after the first medical contact) in 31% of cases, and this delay was the only independent risk factor identified for severe imported malaria in children (adjusted odds ratio, 3.2; 95% CI, 1.2–8.8; P = 0.02).
Keywords: Malaria, Children, Epidemiology, Risk factors
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☆ This study was presented as an abstract at the 27th annual meeting of the European Society for Paediatric Infectious Diseases—ESPID, Brussels, Belgium, June 9 to 12, 2009.
PII: S0732-8893(09)00361-7
doi:10.1016/j.diagmicrobio.2009.08.018
© 2010 Elsevier Inc. All rights reserved.
Volume 66, Issue 2 , Pages 169-174, February 2010
