Diagnostic Microbiology & Infectious Disease
Volume 66, Issue 2 , Pages 228-229, February 2010

A novel OXA-10–like β-lactamase is present in different Enterobacteriaceae☆

  • Ayelén Porto

      Affiliations

    • Cátedra de Microbiología General, Facultad de Bioquímica y Cs. Biológicas, Universidad Nacional del Litoral, 3000 Santa Fe, Argentina
    • ,
  • Juan Ayala

      Affiliations

    • Centro de Biología Molecular “Severo Ochoa”, CSIC-UAM, Campus de Cantoblanco, 28049 Madrid, Spain
    • ,
  • Gabriel Gutkind

      Affiliations

    • Cátedra de Microbiología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, 1113 Buenos Aires, Argentina
    • Corresponding Author InformationCorresponding author. Tel.: +54-11-49648285; fax: +54-11-45083645.
    • ,
  • José Di Conza

      Affiliations

    • Cátedra de Microbiología General, Facultad de Bioquímica y Cs. Biológicas, Universidad Nacional del Litoral, 3000 Santa Fe, Argentina
    • Cátedra de Microbiología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, 1113 Buenos Aires, Argentina

Received 20 May 2009; accepted 9 September 2009. published online 16 October 2009.

Abstract 

OXA 101, a novel OXA-10 like enzyme, was found forming part of a class 1 integron located in a conjugative plasmid in three different species of Enterobacteriaceae. This β-lactamase is related to OXA-35 and OXA-56 and displays a narrow substrate hydrolysis profile.

Keywords: OXA-10 like, Gene cassette, Dissemination

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☆ This manuscript was presented, in part, at the 47th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), 2007.

PII: S0732-8893(09)00375-7

doi:10.1016/j.diagmicrobio.2009.09.010

Diagnostic Microbiology & Infectious Disease
Volume 66, Issue 2 , Pages 228-229, February 2010

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