Epidemiology of pediatric community-acquired bloodstream infections in a children hospital in Paris, France, 2001 to 2008

Received 21 September 2009; accepted 17 October 2009.

Abstract

In 2001 to 2008, we documented 483 cases of pediatric community-acquired bacteremia mostly because of Streptococcus agalactiae (<4 days), Escherichia coli (4 days to 3 months), pneumococci (3 months to 5 years), and Staphylococcus aureus (>5 years). Pneumococcal conjugate vaccination affected the serotype distribution of pneumococcal bacteremia but not its frequency. Serotype 19A represented 12% and 22% of pneumococci in the prevaccine and vaccine periods, respectively.

Keywords: Community-acquired bacteremia, Pneumococcus, PCV-7, Serotype distribution

a Service de Microbiologie, Hôpital Robert-Debré (AP-HP), Université Denis-Diderot-Paris7, 75019 Paris, France

b Centre National de Référence du Pneumocoque, Hôpital Georges Pompidou (AP-HP), 75015 Paris, France

Corresponding author. Service de Microbiologie, Hôpital Robert-Debré, 75395 Paris cedex 19, France. Tel.: +33-1-40-03-23-40; fax: +33-1-40-03-24-50.

PII: S0732-8893(09)00422-2

doi:10.1016/j.diagmicrobio.2009.10.012

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