Diagnostic Microbiology & Infectious Disease
Volume 67, Issue 2 , Pages 117-121 , June 2010

The bacterial load of Ureaplasma parvum in amniotic fluid is correlated with an increased intrauterine inflammatory response

  • David C. Kasper

      Affiliations

    • Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, A-1090 Vienna, Austria
    • Research Core Unit of Pediatric Biochemistry and Analytics, Medical University of Vienna, A-1090 Vienna, Austria
    • Corresponding Author InformationCorresponding author. Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, A-1090 Vienna, Austria. Tel.: +43-1-40400-2756; fax: +43-1-40400-3200.
    • ,
  • Thomas P. Mechtler

      Affiliations

    • Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, A-1090 Vienna, Austria
    • Research Core Unit of Pediatric Biochemistry and Analytics, Medical University of Vienna, A-1090 Vienna, Austria
    • ,
  • Georg H. Reischer

      Affiliations

    • Institute for Chemical Engineering, Gene Technology Group, Vienna University of Technology, A-1060 Vienna, Austria
    • ,
  • Armin Witt

      Affiliations

    • Department of Obstetrics and Gynecology, Medical University of Vienna, A-1090 Vienna, Austria
    • ,
  • Michaela Langgartner

      Affiliations

    • Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, A-1090 Vienna, Austria
    • ,
  • Arnold Pollak

      Affiliations

    • Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, A-1090 Vienna, Austria
    • ,
  • Kurt R. Herkner

      Affiliations

    • Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, A-1090 Vienna, Austria
    • Research Core Unit of Pediatric Biochemistry and Analytics, Medical University of Vienna, A-1090 Vienna, Austria
    • ,
  • Angelika Berger

      Affiliations

    • Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, A-1090 Vienna, Austria

Received 31 October 2009 ,Accepted 30 December 2009.

References 

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  2. Abele-Horn M, Genzel-Boroviczeny O, et al. Ureaplasma urealyticum colonization and bronchopulmonary dysplasia: a comparative prospective multicentre study.. Eur. J. Pediatr. 1998;157(12):1004–1011
  3. Berger A, Witt A, et al. Microbial invasion of the amniotic cavity at birth is associated with adverse short-term outcome of preterm infants.. J. Perinat. Med. 2003;31(2):115–121
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  5. Blanchard A, Hentschel J, et al. Detection of Ureaplasma urealyticum by polymerase chain reaction in the urogenital tract of adults, in amniotic fluid, and in the respiratory tract of newborns.. Clin. Infect. Dis. 1993;17(Suppl 1):S148–S153
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  12. Jacobsson B, Aaltonen R, et al. Quantification of Ureaplasma urealyticum DNA in the amniotic fluid from patients in PTL and pPROM and its relation to inflammatory cytokine levels.. Acta. Obstet. Gynecol. Scand. 2009;88(1):63–70
  13. Kasper DC, Sadeghi K, et al. Quantitative real-time polymerase chain reaction for the accurate detection of Toxoplasma gondii in amniotic fluid.. Diagn. Microbiol. Infect. Dis. 2009;63(1):10–15
  14. Kirchner L, Helmer H, et al. Amnionitis with Ureaplasma urealyticum or other microbes leads to increased morbidity and prolonged hospitalization in very low birth weight infants.. Eur. J. Obstet. Gynecol. Reprod. Biol. 2007;134(1):44–50
  15. Kundsin RB, Leviton A, et al. Ureaplasma urealyticum infection of the placenta in pregnancies that ended prematurely.. Obstet. Gynecol. 1996;87(1):122–127
  16. Mallard K, Schopfer K, et al. Development of real-time PCR for the differential detection and quantification of Ureaplasma urealyticum and Ureaplasma parvum.. J. Microbiol. Methods. 2005;60(1):13–19
  17. Martin-Davila P, Fortun J, et al. Analysis of a quantitative PCR assay for CMV infection in liver transplant recipients: an intent to find the optimal cut-off value.. J. Clin. Virol. 2005;33(2):138–144
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  20. Ollikainen J, Korppi M, et al. Chronic lung disease of the newborn is not associated with Ureaplasma urealyticum.. Pediatr. Pulmonol. 2001;32(4):303–307
  21. Queipo-Ortuno MI, Colmenero JD, et al. Usefulness of a quantitative real-time PCR assay using serum samples to discriminate between inactive, serologically positive and active human brucellosis.. Clin. Microbiol. Infect. 2008;14(12):1128–1134
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  23. Smith-Vaughan H, Byun R, et al. Measuring nasal bacterial load and its association with otitis media.. BMC. Ear. Nose. Throat. Disord. 2006;6:10
  24. Waites KB, Katz B, et al. Mycoplasmas and ureaplasmas as neonatal pathogens.. Clin. Microbiol. Rev. 2005;18(4):757–789
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  27. Witt A, Berger A, et al. Increased intrauterine frequency of Ureaplasma urealyticum in women with preterm labor and preterm premature rupture of the membranes and subsequent cesarean delivery.. Am. J. Obstet. Gynecol. 2005;193(5):1663–1669
  28. Yoon BH, Romero R, et al. Clinical implications of detection of Ureaplasma urealyticum in the amniotic cavity with the polymerase chain reaction.. Am. J. Obstet. Gynecol. 2000;183(5):1130–1137
  29. Yoon BH, Park CW, et al. Intrauterine infection and the development of cerebral palsy.. BJOG. 2003;110(Suppl 20):124–127

PII: S0732-8893(10)00002-7

doi: 10.1016/j.diagmicrobio.2009.12.023

Diagnostic Microbiology & Infectious Disease
Volume 67, Issue 2 , Pages 117-121 , June 2010

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