Diagnostic Microbiology & Infectious Disease
Volume 67, Issue 3 , Pages 277-281 , July 2010

Epidemiology of Escherichia coli clinical isolates producing AmpC plasmidic β-lactamase during a 5-year period in a French teaching Hospital

  • Stéphane Corvec

      Affiliations

    • CHU de Nantes, Service de Bactériologie-Hygiène, 44093 Nantes, France
    • Université de Nantes, EA3826 Thérapeutiques cliniques et expérimentales des infections, UFR de Médecine, 44000 Nantes, France
    • Corresponding Author InformationCorresponding author. CHU de Nantes, Service de Bactériologie-Hygiène, Nantes, France. Tel.: +33-2-40-08-39-55; fax: +33-2-40-08-39-28.
    • ,
  • Lise Crémet

      Affiliations

    • CHU de Nantes, Service de Bactériologie-Hygiène, 44093 Nantes, France
    • ,
  • Céline Leprince

      Affiliations

    • CHU de Nantes, Service de Bactériologie-Hygiène, 44093 Nantes, France
    • ,
  • Sandie Dauvergne

      Affiliations

    • Université de Nantes, EA3826 Thérapeutiques cliniques et expérimentales des infections, UFR de Médecine, 44000 Nantes, France
    • ,
  • Alain Reynaud

      Affiliations

    • CHU de Nantes, Service de Bactériologie-Hygiène, 44093 Nantes, France
    • Université de Nantes, EA3826 Thérapeutiques cliniques et expérimentales des infections, UFR de Médecine, 44000 Nantes, France
    • ,
  • Didier Lepelletier

      Affiliations

    • CHU de Nantes, Service de Bactériologie-Hygiène, 44093 Nantes, France
    • Université de Nantes, EA3826 Thérapeutiques cliniques et expérimentales des infections, UFR de Médecine, 44000 Nantes, France
    • ,
  • Nathalie Caroff

      Affiliations

    • Université de Nantes, EA3826 Thérapeutiques cliniques et expérimentales des infections, UFR de Médecine, 44000 Nantes, France

Received 10 November 2009 ,Accepted 12 February 2010.

References 

  1. Blanco M, Alonso MP, Nicolas-Chanoine M-H, Dahbi G, Mora A, Blanco JE, et al. Molecular epidemiology of Escherichia coli producing extended-spectrum β-lactamases in Lugo (Spain): Dissemination of clone O25b:H4-ST131 producing CTX-M-15. J. Antimicrob. Chemother. 2009;63:1135–1141
  2. Caroff N, Espaze E, Gautreau D, Richet H, Reynaud A. Analysis of the effect of -42 and -32 ampC promoter mutations in clinical isolates of Escherichia coli hyperproducing AmpC. J. Antimicrob. Chemother. 2000;45:783–788
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  4. Corvec S, Prodhomme A, Giraudeau C, Dauvergne S, Reynaud A, Caroff N. Most Escherichia coli strains overproducing chromosomal AmpC β-lactamase belong to phylogenetic group A. J. Antimicrob. Chemother. 2007;60:872–876
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  6. Guillouzouic A, Caroff N, Dauvergne S, Lepelletier D, Perrin Guyomard A, Kempf I, et al. MLST typing of Escherichia coli isolates overproducing AmpC β-lactamase. J. Antimicrob. Chemother. 2009;63:1290–1292
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  9. Jaurin B, Grundstrom T. ampC cephalosporinase of Escherichia coli K-12 has a different evolutionary origin from that of β-lactamases of the penicillinase type. Proc. Natl. Acad. Sci. U. S. A. 1981;78:4897–4901
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  13. Mulvey MR, Bryce E, Boyd DA, Ofner-Agostini M, Land AM, Simor AE, et al. Molecular characterization of cefoxitin-resistant Escherichia coli from Canadian hospitals. Antimicrob. Agents Chemother. 2005;49:358–365
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  15. Noller AC, McEllistrem MC, Stine OC, Morris JG, Boxrud DJ, Dixon B, et al. Multilocus sequence typing reveals a lack of diversity among Escherichia coli O157:H7 isolates that are distinct by pulsed-field gel electrophoresis. J. Clin. Microbiol. 2003;41:675–679
  16. Oteo J, Diestra K, Juan C, Bautista V, Novais A, Pérez-Vasquez M, et al. Extended-spectrum β-lactamase-producing Escherichia coli in Spain belong to a large variety of multilocus sequence typing types, including ST10 complex/A, ST23complex/A and ST131/B2. Int. J. Antimicrob. Agents. 2009;34:173–176
  17. Pérez-Pérez FJ, Hanson ND. Detection of plasmid-mediated AmpC β-lactamase genes in clinical isolates by using multiplex PCR. J. Clin. Microbiol. 2002;40:2153–2162
  18. Sidjabat HE, Paterson DL, Qureshi ZA, Adams-Haduch JM, O'Keefe A, Pascual A, et al. Clinical features and molecular epidemiology of CMY-type β-lactamase-producing Escherichia coli. Clin. Infect. Dis. 2009;48:739–744
  19. Tenover FC, Arbeit RD, Goering RV, Mickelsen PA, Murray BE, Persing DH, et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J. Clin. Microbiol. 1995;33:2233–2239

☆ This work was partially funded by grants from the Ministère de l’Education Nationale et de la Recherche (EA3826), Universités de Nantes, France.

PII: S0732-8893(10)00043-X

doi: 10.1016/j.diagmicrobio.2010.02.007

Diagnostic Microbiology & Infectious Disease
Volume 67, Issue 3 , Pages 277-281 , July 2010

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