Diagnostic Microbiology & Infectious Disease
Volume 67, Issue 3 , Pages 261-265 , July 2010

High prevalence of extended-spectrum β-lactamases and plasmid-mediated AmpC β-lactamases in Enterobacteriaceae isolated from long-term care facilities in Korea

Received 7 December 2009 ,Accepted 12 February 2010.

References 

  1. Achour NB, Mercuri PS, Power P, Belhadj C, Moussa MB, Galleni M, et al. First detection of CTX-M-28 in Tunisian hospital from a cefotaxime-resistant Klebsiella pneumoniae strain. Pathol. Biol. 2009;57:343–348
  2. Apisarnthanrak A, Kiratisin P, Mundy LM. Clinical and molecular epidemiology of healthcare-associated infections due to extended-spectrum β-lactamases (ESBL)–producing strains of Escherichia coli and Klebsiella pneumoniae that harbor multiple ESBL genes. Infect. Control Hosp. Epidemiol. 2008;29:1026–1034
  3. Bonomo RA. Multiple antibiotic-resistant bacteria in long-term-care facilities: an emerging problem in the practice of infectious disease. Clin. Infect. Dis. 2000;31:1414–1422
  4. Clinical and Laboratory Standards Institute (CLSI) . Performance standards for antimicrobial susceptibility testing document, M100-S19. Vol. 29. Wayne, PA: CLSI; 2009;
  5. Hanson ND, Moland ES, Hong SG, Propst K, Novak DJ, Cavalieri SJ. Surveillance of community-based reservoirs reveals the presence of CTX-M, imported AmpC, and OXA-30 β-lactamases in urine isolates of Klebsiella pneumoniae and Escherichia coli in a U.S. community. Antimicrob. Agents Chemother. 2008;52:3814–3816
  6. Heffernan H, Woodhouse R, Pope C, Blackmore T. Prevalence and types of extended-spectrum β-lactamases among urinary Escherichia coli and Klebsiella spp. in New Zealand. Int. J. Antimicrob. Agents. 2009;34:544–549
  7. Kang JH, Bae IK, Kwon SB, Jeong SH, Lee J, et al. Prevalence of Ambler class A extended-spectrum β-lactamase–producing Escherichia coli and Klebsiella pneumoniae isolates in Korea. Korean J. Clin. Microbiol. 2005;8:17–25
  8. Kassis-Chikhani N, Vimont S, Asselat K, Trivalle C, Minassian B, Sengelin C, et al. CTX-M β-lactamase–producing Escherichia coli in long-term care facilities, France. Emerg. Infect. Dis. 2004;10:1697–1698
  9. Kingsley J, Verghese S. Sequence analysis of blaCTX-M-28, an ESBL responsible for third-generation cephalosporin resistance in Enterobacteriaceae, for the first time in India. Indian J. Pathol. Microbiol. 2008;51:218–221
  10. Ko KS, Lee MY, Song JH, Lee H, Jung DS, Jung SI. Prevalence and characterization of extended-spectrum β-lactamase–producing Enterobacteriaceae isolated in Korean hospitals. Diagn. Microbiol. Infect. Dis. 2008;61:453–459
  11. Lee KM, Yoo JI, Yoo YS, Yoo JS, Chung KT, Ahn TI, et al. Investigation of Klebsiella pneumoniae isolates producing SHV-12 and SHV-11 β-lactamases in Korean hospitals. J. Microbiol. Biotechnol. 2009;19:1065–1069
  12. Livermore DM, Canton R, Gniadkowski M, Nordmann P, Rossolini G, Arlet G, et al. CTX-M: changing the face of ESBLs in Europe. J. Antimicrob. Chemother. 2007;59:165–174
  13. Mendelson G, Hait V, Ben-Israel J, Gronich D, Granot E, Raz R. Prevalence and risk factors of extended-spectrum beta-lactamase–producing Escherichia coli and Klebsiella pneumoniae in an Israeli long-term care facility. Eur. J. Clin. Microbiol. Infect. Dis. 2005;24:17–22
  14. Migliavacca R, Nucleo E, D'Andrea M, Spalla M, Giani T, Pagani L. Acquired AmpC type beta-lactamase: an emerging problem in Italian long-term care and rehabilitation facilities. New Microbiol. 2007;30:295–298
  15. Nicolas-Chanoine M, Jarlier V. Extended-spectrum β-lactamases in long-term-care facilities. Clin. Microbiol. Infect. 2008;14:111–116
  16. Oteo J, Navarro C, Cercenado E, Delgado-Iribarren A, Wilhelmi I, Orden B, et al. Spread of Escherichia coli strains with high-level cefotaxime and ceftazidime resistance between the community, long-term care facilities, and hospital institutions. J. Clin. Microbiol. 2006;44:2359–2366
  17. Perez-Perez F, Hanson ND. Detection of plasmid-mediated AmpC β-lactamase genes in clinical isolates by using multiplex PCR. J. Clin. Microbiol. 2002;40:2153–2162
  18. Philippon A, Arlet G, Jacoby G. Plasmid-determined AmpC-type β-lactamases. Antimicrob. Agents Chemother. 2002;46:1–11
  19. Rooney PJ, O'Leary MC, Loughrey AC, McCalmont SB, Donaghy P, Badri M, et al. Nursing homes as a reservoir of extended-spectrum β-lactamase (ESBL)–producing ciprofloxacin-resistant Escherichia coli. J. Antimicrob. Chemother. 2009;64:635–641
  20. Ryoo NH, Kim EC, Hong SG, Park YJ, Lee K, Bae IK, et al. Dissemination of SHV-12 and CTX-M–type extended-spectrum β-lactamases among clinical isolates of Escherichia coli and Klebsiella pneumoniae and emergence of GES-3 in Korea. J. Antimicrob. Chemother. 2005;56:698–702
  21. Shales DM, Gerding DN, John JF, et al. Society for Healthcare Epidemiology of America and the Infectious Disease Society of America Joint Commission on the Prevention of Antimicrobial Resistance: guidelines for the prevention of antimicrobial resistance in hospitals. Infect. Control Hosp. Epidemiol. 1997;18:275–291
  22. Shu JC, Chia JH, Kuo AJ, Su LH, Wu TL. A 7-year surveillance for ESBL-producing Escherichia coli and Klebsiella pneumoniae at a university hospital in Taiwan: the increase of CTX-M-15 in the ICU. Epidemiol. Infect. 2009;21:1–11
  23. Song W, Kim JS, Kim HS, Yong D, Jeong SH, Park MJ, et al. Increasing trend in the prevalence of plasmid-mediated AmpC β-lactamases in Enterobacteriaceae lacking chromosomal ampC gene at a Korean university hospital from 2002 to 2004. Diagn. Microbiol. Infect. Dis. 2006;55:219–224
  24. Song W, Lee H, Lee K, Jeong SH, Bae IK, Kim JS, et al. CTX-M-14 and CTX-M-15 enzymes are the dominant type of extended-spectrum β-lactamase in clinical isolates of Escherichia coli from Korea. J. Med. Microbiol. 2009;58:261–266
  25. Warren RE, Harvey G, Carr R, Ward D, Doroshenko A. Control of infections due to extended-spectrum β-lactamases–producing organisms in hospitals and the community. Clin. Microbiol. Infect. 2008;14:124–133
  26. Yu Y, Ji S, Chen Y, Zhou W, Zm Wei, Li L, et al. Resistance of strains producing extended-spectrum β-lactamases and genotype distribution in China. J. Infect. 2007;54:53–57
  27. Yum JH, Kim S, Lee H, Yong D, Lee K, Cho SN, et al. Emergence and wide dissemination of CTX-M–type ESBLs, and CMY-2- and DHA-1–type AmpC β-lactamases in Korean respiratory isolates of Klebsiella pneumoniae. J. Korean Med. Sci. 2005;20:961–965

PII: S0732-8893(10)00048-9

doi: 10.1016/j.diagmicrobio.2010.02.012

Diagnostic Microbiology & Infectious Disease
Volume 67, Issue 3 , Pages 261-265 , July 2010