Diagnostic Microbiology & Infectious Disease
Volume 67, Issue 4 , Pages 380-383, August 2010

High percentage of resistance to ciprofloxacin and qnrB19 gene identified in urinary isolates of extended-spectrum β-lactamase–producing Escherichia coli in Madrid, Spain☆

Servicio de Microbiología, Hospital Clínico San Carlos, 28040 Madrid, Spain

Received 16 December 2009; accepted 16 March 2010.

Abstract 

The presence of qnr genes in 191 extended-spectrum β-lactamase–producing Escherichia coli from 2005, with 75% of resistance to ciprofloxacin, was evaluated. An SHV-12–producing E. coli carried qnrB19; both genes were transferred by conjugation. No qnrA- or qnrS-positive strains were detected. In addition, we identified 3 new parC mutations (S80W, E84R, and E84A).

Keywords: qnr, E. coli, Fluoroquinolone, Resistance

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

☆ This work was presented at the 19th European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Helsinki, Finland, May 2009.

PII: S0732-8893(10)00091-X

doi:10.1016/j.diagmicrobio.2010.03.007

Diagnostic Microbiology & Infectious Disease
Volume 67, Issue 4 , Pages 380-383, August 2010

Article Tools